The story begins at the opening of the 16th century with Arrejedhuys, a plot of land in the ownership of the Roustaing family. With the sale of this land in 1540 to a local merchant, Arnaut de Lestonnac, we have the genesis of La Mission Haut-Brion.
In 1919, Victor Cousteau bought the estate which opened the way for new investment and a deserved updating of the property; this was the start of La Mission Haut-Brion's modern era.